While government officials are targeted in the sweeping anti-corruption drive, clock is also ticking for some foreign companies.
Over 20 people including four senior executives from the British pharmaceutical company GlaxoSmithKline (GSK) were detained in connection with serious economic crimes.
Police said GSK has bribed government officials, pharmaceutical industry associations, hospitals and doctors directly or indirectly in order to increase sales or raise drug prices.
Some Chinese doctors revealed that it has become a "hidden rule" for many pharmaceuticals salespeople to offer bribes to medics.
The National Development and Reform Commission (NDRC) examined 27 companies on production costs and 33 for pricing including Merck, Astellas, Novartis' generics unit Sandoz, Boehringer Ingelheim, Baxter International and Fresenius.
The NDRC also investigated potential price-fixing and anti-competitive conducts by five instant milk powder makers, including Swiss company Nestle and French rival Danone.
Starbucks and Apple were also under media criticism for charging Chinese customers higher prices than other markets. "Chastising Starbucks is not as meaningful as introspecting on why we don't have a Chinese tea house chain that is as popular as Starbucks," Xinhua's official Weibo commented.